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Brief Overview of the Women's Health Initiative Study
After a woman has a hysterectomy, her doctor will start
her on a hormone replacement therapy (HRT). This is
simply a treatment that's designed to replace the hormones
that will be lost through the hysterectomy; it staves
off certain medical conditions including menopause and
osteoporosis.
Hormone replacement therapy treatments use synthetic
hormones that are designed in laboratories instead of
a woman's body. However, those synthetic hormones will
act like the natural hormones she has in her body.
Years ago doctors would prescribe HRT, hoping it would
protect the woman from certain diseases along with treating
any menopause symptoms. Some of the diseases that doctors
were hoping to prevent included:
- Cancer
- Heart disease
- Osteoporosis
For some women, the benefits outweigh the risks; for
other woman, the risks outweigh the benefits. Women
need to speak with their doctor about the hormone replacement
therapy to see if it is good for them.
An Overview of the Women's Health Initiative
The National Institutes of Health conducted a set of
studies dubbed the Women's Health Initiative. Researchers
for the WHI gathered together information about women
who have gone through menopause, as well as information
about these women's overall health. The reason behind
the HRT trial was to study the effects of the therapy
on a woman's health, and to see if the woman developed
breast and/or colorectal cancers, heart disease or osteoporosis
once she had been through menopause.
Whom Did the Study Involve?
There were two groups of women involved with the trial.
Women who have undergone a hysterectomy were in one
group. Women who were postmenopausal with no hysterectomy
were in the other group.
The first group was given a placebo or estrogen during
the trial. The second group took a combination of estrogen
and progestin or the placebo.
Trial Stopped Due to Complications
The trial was to end in 2005. However, in 2002, the
combination therapy was halted due to risks that were
found with combination HRT. Those risks outweighed the
benefits that were supposed to result from the HRT trial.
What kinds of risks were found? Women who used HRT
over a long period of time were found to be prone to
blood clots, breast cancer, heart attacks and strokes.
People Who Are Taking HRT Currently
Women should never stop taking their medications without
first speaking with their doctor. If she is concerned
about the risks, her doctor will consider the symptoms,
and will consider whether or not the woman is at risk
for developing any diseases based on the medication.
If there's too much of a risk, there are three things
the doctor may choose to do. They are:
- Lowering the dose of medicine
- Switching to another kind of treatment
- Stopping the current treatment altogether
Unless there is a big risk, a woman's current treatment
is likely to stay the same.
Using HRT For Long-Term Use
Should a woman consider using hormone replacement therapy
for long-term use? This question can be answered with
a simple deduction. First, a woman should understand
that HRT does offer protection against certain kinds
of illnesses such as colorectal cancer, Alzheimer's
disease and osteoporosis.
If a woman's risks of developing the above diseases
is high and she has little to no chance of developing
breast cancer and/or heart disease, then HRT can be
quite effective for long-term use.
It's very important that a woman and her doctor talk
about the risks and benefits of HRT.
Can Menopausal Symptoms Be Treated With Any Other
Options?
If you wish not to do hormone replacement therapy,
there are other alternatives. For instance, there are
antidepressants, herbal supplements, soy products and
vaginal estrogen creams. There are also more medications
on the market that a woman's doctor can prescribe. By
talking with her doctor, the two together can discern
what treatment is best.
One of the more important things to remember is to
maintain a healthy weight by eating healthy and exercise
on a regular basis.
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